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1

Novel oxathiazinones as gastrin ligands : Unexpected preducts from the schotten-baumann reaction of arylsulphonyl chlorides with derivatives of aspartic acid

Caroline M.R. Low, Howard B. Broughton, S.Barret Kalindjian, Iain M. McDonald

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1992

Language:

english

File:

PDF, 407 KB

english, 1992

2

DPPE: A convenient replacement for triphynylphosphine in the staudinger and Mitsunobu reactions

Ian A. O'Neil, Stephen Thompson, Clare L. Murray, S.Barret Kalindjian

Journal:

Tetrahedron Letters

Year:

1998

Language:

english

File:

PDF, 202 KB

english, 1998

3

A Cyclobutadiene Equivalent in the Catalytic Pauson–Khand Reaction

Susan E. Gibson, Nello Mainolfi, S. Barret Kalindjian, Paul T. Wright

Journal:

Angewandte Chemie

Year:

2004

Language:

english

File:

PDF, 128 KB

english, 2004

4

A Cyclobutadiene Equivalent in the Catalytic Pauson–Khand Reaction

Susan E. Gibson, Nello Mainolfi, S. Barret Kalindjian, Paul T. Wright

Journal:

Angewandte Chemie International Edition

Year:

2004

Language:

english

File:

PDF, 128 KB

english, 2004

5

A New Class of Non-Racemic Chiral Macrocycles: A Conformational and Synthetic Study

Susan E. Gibson, Nello Mainolfi, S. Barret Kalindjian, Paul T. Wright, Andrew J. P. White

Journal:

Chemistry - A European Journal

Year:

2005

Language:

english

File:

PDF, 468 KB

english, 2005

6

ChemInform Abstract: From Histamine to Imidazolylalkyl-sulfonamides: The Design of a Novel Series of Histamine H3-Receptor Antagonists.

Matthew J. Tozer, Elaine A. Harper, S. Barret Kalindjian, Michael J. Pether, Nigel P. Shankley, Gillian F. Watt

Journal:

Year:

1999

File:

PDF, 34 KB

1999

7

ChemInform Abstract: 4-Chlorobenzyl Sulfonamide and Sulfamide Derivatives of Histamine Homologues: The Design of Potent Histamine H3 Receptor Antagonists.

Matthew J. Tozer, Ildiko M. Buck, Tracey Cooke, S. Barret Kalindjian, Iain M. McDonald, Michael J. Pether, Katherine I. M. Steel

Journal:

Year:

2000

File:

PDF, 32 KB

2000

8

ChemInform Abstract: Design, Synthesis, and Structure—Activity Relationships of Novel Non-Imidazole Histamine H3 Receptor Antagonists.

Ian D. Linney, Ildiko M. Buck, Elaine A. Harper, S. Barret-Kalindjian, Michael J. Pether, Nigel P. Shankley, Gillian F. Watt, Paul T. Wright

Journal:

Year:

2000

File:

PDF, 35 KB

2000

9

ChemInform Abstract: Synthesis and Applications of Conformationally Constrained Phenylalanine Analogues

Susan E. Gibson, Nathalie Guillo, S. Barret Kalindjian, Matthew J. Tozer, Nicole J. Whitcombe

Journal:

Year:

2000

File:

PDF, 25 KB

2000

10

ChemInform Abstract: ω-(Imidazol-4-yl)alkane-1-sulfonamide: A New Series of Potent Histamine H3 Receptor Antagonists.

Matthew J. Tozer, Ildiko M. Buck, Tracey Cooke, S. Barret Kalindjian, Michael J. Pether, Katherine I. M. Steel

Journal:

Year:

2002

File:

PDF, 38 KB

2002

11

CCK2 Receptor Antagonists Containing the Conformationally Constrained Phenylalanine Derivatives, Including the New Amino Acid Xic.

Susan E. Gibson, Nathalie Guillo, Jerome O. Jones, Ildiko M. Buck, S. Barret Kalindjian, Sonia Roberts, Matthew J. Tozer

Journal:

Year:

2002

Language:

english

File:

PDF, 37 KB

english, 2002

12

Synthesis and Structural Analysis of Dehydrophenylalanine Cyclophanes.

Susan E. Gibson, Jerome O. Jones, S. Barret Kalindjian, Jamie D. Knight, Jonathan W. Steed, Matthew J. Tozer

Journal:

Year:

2002

File:

PDF, 27 KB

2002

13

A Versatile Approach to Chiral Macrocycles.

Susan E. Gibson, Nello Mainolfi, S. Barret Kalindjian, Paul T. Wright

Journal:

Year:

2003

File:

PDF, 133 KB

2003

14

The Synthesis and Biological Activity of C2-Fluorinated Pyrrolo[2,1-c][1,4]benzodiazepines.

Ian A. O'Neil, Stephen Thompson, S. Barret Kalindjian, Terence C. Jenkins

Journal:

Year:

2004

File:

PDF, 125 KB

2004

15

The Diastereoselective Synthesis of Functionalized Isoxazolidines Using a Cope Elimination/Intramolecular Nitrone Cycloaddition Strategy.

Ian A. O'Neil, V. Elena Ramos, Gemma L. Ellis, Ed Cleator, Alan P. Chorlton, David J. Tapolczay, S. Barret Kalindjian

Journal:

Year:

2004

File:

PDF, 84 KB

2004

16

A Cyclobutadiene Equivalent in the Catalytic Pauson—Khand Reaction.

Susan E. Gibson, Nello Mainolfi, S. Barret Kalindjian, Paul T. Wright

Journal:

Year:

2005

File:

PDF, 21 KB

2005

17

The synthesis of a radioligand with high potency and selectivity for CCKB/ gastrin receptors

S.Barret Kalindjian, Elaine A. Harper, Michael J. Pether

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1996

Language:

english

File:

PDF, 190 KB

english, 1996

18

The synthesis and biological activity of C2-fluorinated pyrrolo[2,1-c][1,4]benzodiazepines

Ian A. O'Neil, Stephen Thompson, S.Barret Kalindjian, Terence C. Jenkins

Journal:

Tetrahedron Letters

Year:

2003

Language:

english

File:

PDF, 135 KB

english, 2003

19

The diastereoselective synthesis of functionalised isoxazolidines using a Cope elimination/intramolecular nitrone cycloaddition strategy

Ian A O'Neil, V.Elena Ramos, Gemma L Ellis, Ed Cleator, Alan P Chorlton, David J Tapolczay, S.Barret Kalindjian

Journal:

Tetrahedron Letters

Year:

2004

Language:

english

File:

PDF, 250 KB

english, 2004

20

The synthesis of functionalised chiral bicyclic lactam and lactone N-oxides using a tandem Cope elimination/reverse Cope elimination protocol

Gemma L. Ellis, Ian A. O’Neil, V. Elena Ramos, Ed Cleator, S. Barret Kalindjian, Alan P. Chorlton, David J. Tapolczay

Journal:

Tetrahedron Letters

Year:

2007

Language:

english

File:

PDF, 147 KB

english, 2007

21

The diastereoselective synthesis of functionalised spirocyclic lactams and lactones using a Cope elimination/intramolecular nitrone cycloaddition strategy

Gemma L. Ellis, Ian A. O’Neil, V. Elena Ramos, S. Barret Kalindjian, Alan P. Chorlton, David J. Tapolczay

Journal:

Tetrahedron Letters

Year:

2007

Language:

english

File:

PDF, 137 KB

english, 2007

22

The synthesis of a novel benzodiazocine via an intramolecular Staudinger/aza-Wittig cyclization

Ian A O'Neil, Clare L Murray, Andrew J Potter, S.Barret Kalindjian

Journal:

Tetrahedron Letters

Year:

1997

Language:

english

File:

PDF, 117 KB

english, 1997

23

CCK2 receptor antagonists containing the conformationally constrained phenylalanine derivatives, including the new amino acid Xic

Susan E Gibson (née Thomas), Nathalie Guillo, Jerome O Jones, Ildiko M Buck, S.Barret Kalindjian, Sonia Roberts, Matthew J Tozer

Journal:

European Journal of Medicinal Chemistry

Year:

2002

Language:

english

File:

PDF, 366 KB

english, 2002

24

2-NAP: a selective, hydrophilic, non-peptide CCKA - receptor antagonist derived from the cholecystokinin C-terminal dipeptide.

Iain M. McDonald, Michael J. Bodkin, Howard B. Broughton, David J. Dunstone, S.Barret Kalindjian, Caroline M.R. Low

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1993

Language:

english

File:

PDF, 444 KB

english, 1993

25

INCORPORATION OF CONFORMATIONALLY CONSTRAINED PHENYLALANINE DERIVATIVES TIC, SIC, HIC AND NIC INTO A CHOLECYSTOKININ-B/GASTRIN RECEPTOR ANTAGONIST

Susan E Gibson, Nathalie Guillo, S.Barret Kalindjian, Matthew J Jozer

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1997

Language:

english

File:

PDF, 499 KB

english, 1997

26

From histamine to imidazolylalkyl-sulfonamides: The design of a novel series of histamine H3-receptor antagonists

Matthew J. Tozer, Elaine A. Harper, S.Barret Kalindjian, Michael J. Pether, Nigel P. Shankley, Gillian F. Watt

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1999

Language:

english

File:

PDF, 337 KB

english, 1999

27

4-Chlorobenzyl sulfonamide and sulfamide derivatives of histamine homologues: The design of potent histamine H3 receptor antagonists

Matthew J. Tozer, Ildiko M. Buck, Tracey Cooke, S.Barret Kalindjian, Iain M. McDonald, Michael J. Pether, Katherine I.M. Steel

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1999

Language:

english

File:

PDF, 306 KB

english, 1999

28

Gastrin Agonists and Antagonists

James W. Black, S. Barret Kalindjian

Journal:

Basic & Clinical Pharmacology & Toxicology

Year:

2002

Language:

english

File:

PDF, 294 KB

english, 2002

29

Synthesis of meta- and paracyclophanes containing unsaturated amino acid residues

Susan E. Gibson, Jerome O. Jones, S.Barret Kalindjian, Jamie D. Knight, Nello Mainolfi, Matthew Rudd, Jonathan W. Steed, Matthew J. Tozer, Paul T. Wright

Journal:

Year:

2004

Language:

english

File:

PDF, 690 KB

english, 2004

30

ω-(Imidazol-4-yl)alkane-1-sulfonamides: a new series of potent histamine H3 receptor antagonists

Matthew J. Tozer, Ildiko M. Buck, Tracey Cooke, S.Barret Kalindjian, Michael J. Pether, Katherine I.M. Steel

Journal:

Bioorganic & Medicinal Chemistry

Year:

2002

Language:

english

File:

PDF, 168 KB

english, 2002

31

2,7-Dioxo-2,3,4,5,6,7-hexahydro-1H-benzo[h][1,4]diazonine as a New Template for the Design of CCK2 Receptor Antagonists

McDonald, Iain M., Dunstone, David J., Kalindjian, S. Barret, Pether, Michael J., Steel, Katherine I. M., Tozer, Matthew J., Vinter, J. G., Linney, Ian D., Low, Caroline M. R.

Journal:

Journal of Medicinal Chemistry

Year:

2000

Language:

english

File:

PDF, 280 KB

english, 2000

32

The preparation and properties of novel reversible polymer-protein conjugates 2-ω-Methoxypolyethylene (5000) glycoxymethylene-3-methylmaleyl conjugates of plasminogen activators

Andrew J. Garman, S. Barret Kalindjian

Journal:

Year:

1987

Language:

english

File:

PDF, 442 KB

english, 1987

33

Scaffold Hopping with Molecular Field Points: Identification of a Cholecystokinin-2 (CCK 2 ) Receptor Pharmacophore and Its Use in the Design of a Prototypical Series of Pyrrole- and Imidazole-Based CCK 2 Antagonists

Low, Caroline M. R., Buck, Ildiko M., Cooke, Tracey, Cushnir, Julia R., Kalindjian, S. Barret, Kotecha, Atul, Pether, Michael J., Shankley, Nigel P., Vinter, J. G., Wright, Laurence

Journal:

Journal of Medicinal Chemistry

Year:

2005

Language:

english

File:

PDF, 275 KB

english, 2005

34

Nonpeptide Cholecystokinin-2 Receptor Agonists

Kalindjian, S. Barret, Dunstone, David J., Low, Caroline M. R., Pether, Michael J., Roberts, Sonia P., Tozer, Matthew J., Watt, Gillian F., Shankley, Nigel P.

Journal:

Journal of Medicinal Chemistry

Year:

2001

Language:

english

File:

PDF, 256 KB

english, 2001

35

Optimization of the in Vitro and in Vivo Properties of a Novel Series of 2,4,5-Trisubstituted Imidazoles as Potent Cholecystokinin-2 (CCK 2 ) Antagonists

Buck, Ildiko M., Black, James W., Cooke, Tracey, Dunstone, David J., Gaffen, John D., Griffin, Eric P., Harper, Elaine A., Hull, Robert A. D., Kalindjian, S. Barret, Lilley, Elliot J., Linney, Ian D.,

Journal:

Journal of Medicinal Chemistry

Year:

2005

Language:

english

File:

PDF, 156 KB

english, 2005

36

Discovery and Characterization of Novel, Potent, Non-Peptide Parathyroid Hormone-1 Receptor Antagonists

McDonald, Iain M., Austin, Carol, Buck, Ildiko M., Dunstone, David J., Gaffen, John, Griffin, Eric, Harper, Elaine A., Hull, Robert A. D., Kalindjian, S. Barret, Linney, Ian D., Low, Caroline M. R., P

Journal:

Journal of Medicinal Chemistry

Year:

2007

Language:

english

File:

PDF, 65 KB

english, 2007

37

A New Class of Non-peptidic Cholecystokinin-B/Gastrin Receptor Antagonists Based on Dibenzobicyclo[2.2.2]octane

Kalindjian, S. Barret, Bodkin, Michael J., Buck, Ildiko M., Dunstone, David J., Low, Caroline M. R., McDonald, Iain M., Pether, Michael J., Steel, Katherine I. M.

Journal:

Journal of Medicinal Chemistry

Year:

1994

Language:

english

File:

PDF, 378 KB

english, 1994

38

Development of Peptide 3D Structure Mimetics: Rational Design of Novel Peptoid Cholecystokinin Receptor Antagonists

Low, Caroline M. R., Black, James W., Broughton, Howard B., Buck, Ildiko M., Davies, Jonathan M. R., Dunstone, David J., Hull, Robert A. D., Kalindjian, S. Barret, McDonald, Iain M., Pether, Michael J

Journal:

Journal of Medicinal Chemistry

Year:

2000

Language:

english

File:

PDF, 236 KB

english, 2000

39

Novel, Achiral 1,3,4-Benzotriazepine Analogues of 1,4-Benzodiazepine-Based CCK 2 Antagonists That Display High Selectivity over CCK 1 Receptors

McDonald, Iain M., Austin, Carol, Buck, Ildiko M., Dunstone, David J., Griffin, Eric, Harper, Elaine A., Hull, Robert A. D., Kalindjian, S. Barret, Linney, Ian D., Low, Caroline M. R., Pether, Michael

Journal:

Journal of Medicinal Chemistry

Year:

2006

Language:

english

File:

PDF, 150 KB

english, 2006

40

Optimization of 1,3,4-Benzotriazepine-Based CCK 2 Antagonists to Obtain Potent, Orally Active Inhibitors of Gastrin-Mediated Gastric Acid Secretion

McDonald, Iain M., Black, James W., Buck, Ildiko M., Dunstone, David J., Griffin, Eric P., Harper, Elaine A., Hull, Robert A. D., Kalindjian, S. Barret, Lilley, Elliot J., Linney, Ian D., Pether, Mich

Journal:

Journal of Medicinal Chemistry

Year:

2007

Language:

english

File:

PDF, 322 KB

english, 2007

41

Improving the Affinity and Selectivity of a Nonpeptide Series of Cholecystokinin-B/Gastrin Receptor Antagonists Based on the Dibenzobicyclo[2.2.2]octane Skeleton

Kalindjian, S. Barret, Buck, Ildiko M., Cushnir, Julia R., Dunstone, David J., Hudson, Martin L., Low, Caroline M. R., McDonald, Iain M., Pether, Michael J., Steel, Katherine I. M., Tozer, Matthew J.

Journal:

Journal of Medicinal Chemistry

Year:

1995

Language:

english

File:

PDF, 1.05 MB

english, 1995

42

Design, Synthesis, and Structure−Activity Relationships of Novel Non-Imidazole Histamine H 3 Receptor Antagonists

Linney, Ian D., Buck, Ildiko M., Harper, Elaine A., Kalindjian, S. Barret, Pether, Michael J., Shankley, Nigel P., Watt, Gillian F., Wright, Paul T.

Journal:

Journal of Medicinal Chemistry

Year:

2000

Language:

english

File:

PDF, 177 KB

english, 2000

43

Development of a Scalable Synthesis of Gastrazole (JB95008): A Potent CC K 2 Receptor Antagonist

Ormerod, Dominic, Willemsens, Bert, Mermans, Rit, Langens, Jaak, Winderickx, Guy, Kalindjian, S. Barret, Buck, Ildiko M., McDonald, Iain M.

Journal:

Organic Process Research & Development

Year:

2005

Language:

english

File:

PDF, 143 KB

english, 2005

44

Non-Peptide Cholecystokinin-B/Gastrin Receptor Antagonists Based on Bicyclic, Heteroaromatic Skeletons

Kalindjian, S. Barret, Buck, Ildiko M., Davies, Jonathan M. R., Dunstone, David J., Hudson, Martin L., Low, Caroline M. R., McDonald, Iain M., Pether, Michael J., Steel, Katherine I. M., Tozer, Matthe

Journal:

Journal of Medicinal Chemistry

Year:

1996

Language:

english

File:

PDF, 486 KB

english, 1996

45

Synthesis and structural analysis of dehydrophenylalanine cyclophanes

Gibson (n??e Thomas), Susan E., Jones, Jerome O., Kalindjian, S. Barret, Knight, Jamie D., Steed, Jonathan W., Tozer, Matthew J.

Journal:

Chemical Communications

Year:

2002

Language:

english

File:

PDF, 189 KB

english, 2002

46

Inclusion complexation of 1,4-dioxan by an azaparcyclophane; an X-ray crystallographic study

Abbott, Stephen J., Barrett, Anthony G. M., Godfrey, Christopher R. A., Kalindjian, S. Barret, Simpson, Gregory W., Williams, David J.

Journal:

Journal of the Chemical Society Chemical Communications

Year:

1982

Language:

english

File:

PDF, 198 KB

english, 1982

47

A versatile approach to chiral macrocycles

Gibson, Susan E., Mainolfi, Nello, Barret Kalindjian, S., Wright, Paul T.

Journal:

Chemical Communications

Year:

2003

Language:

english

File:

PDF, 123 KB

english, 2003

48

Histamine H 3 receptor antagonists

Tozer, Matthew J, Kalindjian, S Barret

Journal:

Expert Opinion on Therapeutic Patents

Year:

2000

Language:

english

File:

PDF, 151 KB

english, 2000

49

Strategies for the Design of Non-peptide CCK2 Receptor Agonist and Antagonist Ligands

S. Barret Kalindjian, Bentham Science Publisher, Iain M. McDonald, Bentham Science Publisher

Journal:

Current Topics in Medicinal Chemistry

Year:

2007

Language:

english

File:

PDF, 223 KB

english, 2007

50

The Novel Use of Proline Derived Amine Oxides in Controlling Amide Conformation

O'Neil, Ian A., Miller, Neil D., Peake, Julie, Barkley, Jim V., Low, Caroline M. R., Kalindjian, S. Barret

Journal:

Year:

1993

File:

PDF, 217 KB

1993